KAWASAKI DISEASE IN KAZAKHSTAN: AN UNMET CLINICAL AND PUBLIC HEALTH ISSUE?

Dimitri Poddighe; Bakhtiyar Azhken

doi:10.47316/cajmhe.2020.1.1.03

Dimitri Poddighe Department of Medicine, Nazarbayev University School of Medicine, Nur-Sultan Kazakhstan https://orcid.org/0000-0001-6431-9334
Bakhtiyar Azhken Department of General Medical Practice, Astana Medical University, Nur-Sultan, Kazakhstan https://orcid.org/0000-0002-7664-457X

DOI: https://doi.org/10.47316/cajmhe.2020.1.1.03

Keywords: Kawasaki disease, Mucocutaneous lymph node syndrome, Coronary aneurysm, Intravenous immunoglobulin, Kazakhstan, Central Asia, Hypothesis

Abstract

Kawasaki disease (KD) is a systemic vasculitis targeting medium-sized and small arteries. It manifests in young children. If not appropriately treated, KD leads to the development of coronary artery aneurysms inabout 20% of patients. No local evidence-based clinical and epidemiological data on KD are currently available in Kazakhstan. The awareness of KD among physicians is inadequate, resulting in underdiagnosis of the disease in the country. Given the high priority of cardiovascular morbidity and mortality in Central Asian countries, clinical and epidemiological studies on KD along with measures for early diagnosis and management of the patients with cardiovascular affections are warranted.

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